A Family History Study of Neuropsychiatric Disorders in the Adult Siblings of Autistic Individuals

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) h...

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Veröffentlicht in:	Journal of the American Academy of Child and Adolescent Psychiatry 1990-03, Vol.29 (2), p.177-183
Hauptverfasser:	PIVEN, JOSEPH, GAYLE, JEANNE, CHASE, GARY A., FINK, BARBIE, LANDA, REBECCA, WZOREK, MARYANN M., FOLSTEIN, SUSAN E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adult and adolescent clinical studies affective disorder autism Autistic Disorder - genetics Biological and medical sciences Child cognitive disorder Female Fragile X Syndrome - genetics genetics Humans Intelligence Male Medical sciences Neurocognitive Disorders - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Risk Factors Social Adjustment
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Beschreibung
Zusammenfassung:	The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals.
ISSN:	0890-8567 1527-5418
DOI:	10.1097/00004583-199003000-00004