Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites

Microsatellite instability (MI) characterizing tumors with replication errors (RER+ tumors) was first described in colorectal tumors from hereditary non‐polyposis colorectal cancer (HNPCC) patients as well as in sporadic cases. It has also been observed in subgroups of extracolonic sporadic tumors,...

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Veröffentlicht in:Genes chromosomes & cancer 1998-02, Vol.21 (2), p.101-107
Hauptverfasser: Zhou, Xiao-Ping, Hoang, Jean-Marc, Li, You-Jun, Seruca, Raquel, Carneiro, Fatima, Sobrinho-Simoes, Manuel, Lothe, Ragnhild A., Gleeson, Catherine M., Russell, S.E. Hilary, Muzeau, Françoise, Fléjou, Jean-François, Hoang-Xuan, Khê, Lidereau, Rosette, Thomas, Gilles, Hamelin, Richard
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Sprache:eng
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