Community-Acquired Methicillin-Resistant Staphylococcus aureus in Children With No Identified Predisposing Risk
CONTEXT.— Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections in children have occurred primarily in individuals with recognized predisposing risks. Community-acquired MRSA infections in the absence of identified risk factors have been reported infrequently. OBJECTIVES.—...
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Veröffentlicht in: | JAMA : the journal of the American Medical Association 1998-02, Vol.279 (8), p.593-598 |
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Sprache: | eng |
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Zusammenfassung: | CONTEXT.— Community-acquired methicillin-resistant Staphylococcus
aureus (MRSA) infections in children have occurred primarily in individuals
with recognized predisposing risks. Community-acquired MRSA infections in
the absence of identified risk factors have been reported infrequently. OBJECTIVES.— To determine whether community-acquired MRSA infections in children
with no identified predisposing risks are increasing and to define the spectrum
of disease associated with MRSA isolation. DESIGN.— Retrospective review of medical records. PATIENTS.— Hospitalized children with S aureus isolated
between August 1988 and July 1990 (1988-1990) and between August 1993 and
July 1995 (1993-1995). SETTING.— The University of Chicago Children's Hospital. MAIN OUTCOME MEASURES.— Prevalence of community-acquired MRSA over time, infecting vs colonizing
isolates, and risk factors for disease. RESULTS.— The number of children hospitalized with community-acquired MRSA disease
increased from 8 in 1988-1990 to 35 in 1993-1995. Moreover, the prevalence
of community-acquired MRSA without identified risk increased from 10 per 100000
admissions in 1988-1990 to 259 per 100000 admissions in 1993-1995 (P |
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ISSN: | 0098-7484 1538-3598 |
DOI: | 10.1001/jama.279.8.593 |