Induction of multifocal pancreatic cancer after inoculation of hamster pancreatic cancer cell line (PC-1) into a defined area of homologous pancreatic tissue

Inoculation of the pancreatic cancer cell line PC-1 into a defined area of the tail of the hamster pancreas led to development of multiple cancerous foci in the body of the pancreas along the main pancreatic duct. Each carcinoma showed identical histological characteristics and was completely separa...

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Veröffentlicht in:	Cancer letters 1990-04, Vol.50 (1), p.53-56
Hauptverfasser:	Egami, H., Takiyama, Y., Pour, P.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Biological and medical sciences cell line Cricetinae experimental Experimental digestive system and abdominal tumors intrapancreatic Medical sciences Mesocricetus Neoplasm Transplantation pancreatic cancer Pancreatic Neoplasms - etiology Pancreatic Neoplasms - pathology Syrian hamster transplantation Tumor Cells, Cultured Tumors
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Zusammenfassung:	Inoculation of the pancreatic cancer cell line PC-1 into a defined area of the tail of the hamster pancreas led to development of multiple cancerous foci in the body of the pancreas along the main pancreatic duct. Each carcinoma showed identical histological characteristics and was completely separated from the others by regions of normal pancreatic tissue. This observation suggests spread of the cancer from the primary site in discontinuity through the ductal system of the pancreas.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/0304-3835(90)90178-Z