Protective prion protein polymorphisms against sporadic Creutzfeldt-Jakob disease

Protective prion protein polymorphisms against sporadic Creutzfeldt-Jakob disease

A study indicates that the codon 219Glu/Lys heterozygous polymorphism of the PrP gene is likely to serve as a protecting factor against sporadic Creutzfeldt-Jakob disease.

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Bibliographische Detailangaben
Veröffentlicht in:The Lancet (British edition) 1998-02, Vol.351 (9100), p.419-419
Hauptverfasser: Shibuya, S, Higuchi, J, Shin, R-W, Tateishi, J, Kitamoto, T
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Codon - genetics
Creutzfeldt-Jakob disease
Creutzfeldt-Jakob Syndrome - genetics
Creutzfeldt-Jakob Syndrome - metabolism
Disease
Genes
Human viral diseases
Humans
Infectious diseases
Medical research
Medical sciences
Polymorphism, Genetic
Prions - genetics
Viral diseases
Viral diseases of the nervous system
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Beschreibung
Zusammenfassung:A study indicates that the codon 219Glu/Lys heterozygous polymorphism of the PrP gene is likely to serve as a protecting factor against sporadic Creutzfeldt-Jakob disease.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)78358-6