Phenylethanolamine N-methyltransferase mRNA in rat hypothalamus and cerebellum

Phenylethanolamine N-methyltransferase mRNA in rat hypothalamus and cerebellum

Using the reverse transcription polymerase chain reaction, we detected a single form of phenylethanolamine N-methyltransferase (PNMT) mRNA in hypothalamus and medulla/pons and two forms in cerebellum. These findings indicate that the PNMT gene is expressed in these brain areas and suggest that tissu...

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Veröffentlicht in:Brain research 1998, Vol.779 (1), p.289-291
Hauptverfasser: Andreassi, John L, Eggleston, William B, Fu, Guillian, Stewart, Jennifer K
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Catecholamine
Cerebellum - chemistry
Hypothalamus
Hypothalamus - chemistry
Male
Medulla Oblongata - chemistry
mRNA
Phenylethanolamine N-Methyltransferase - genetics
PNMT
Polymerase Chain Reaction - methods
Pons - chemistry
Rat
Rats
Rats, Sprague-Dawley
RNA, Messenger - analysis
RT-PCR
Transcription, Genetic
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Zusammenfassung:Using the reverse transcription polymerase chain reaction, we detected a single form of phenylethanolamine N-methyltransferase (PNMT) mRNA in hypothalamus and medulla/pons and two forms in cerebellum. These findings indicate that the PNMT gene is expressed in these brain areas and suggest that tissue specific splicing of PNMT mRNA may occur.
ISSN:0006-8993
1872-6240
DOI:10.1016/S0006-8993(97)01170-0