Removal of Methylene Blue from Plasma via an Adsorbent Filter

Objective: To evaluate adsorbent filtration of methylene blue (MB) and leukocytes from plasma. Methods: Plasma (750 ml) from apheresis of 10 normal subjects was split into three aliquots: control (A), filtration (B) and MB addition (to 1 μM), phototreatment and filtration (C). Biochemical and coagul...

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Veröffentlicht in:	Vox sanguinis 1998-01, Vol.74 (1), p.1-6
Hauptverfasser:	AuBuchon, James P., Pickard, Constance, Herschel, Louise, O'Connor, James L., Lee, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Transfusion, Autologous Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Female Fibrinogen - analysis Filtration - instrumentation Filtration - methods Hematologic Tests Humans Leukocyte Count Male Medical sciences Methylene Blue - analysis Partial Thromboplastin Time Plasma - chemistry Plasma - virology Prothrombin Time Reference Values Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Zusammenfassung:	Objective: To evaluate adsorbent filtration of methylene blue (MB) and leukocytes from plasma. Methods: Plasma (750 ml) from apheresis of 10 normal subjects was split into three aliquots: control (A), filtration (B) and MB addition (to 1 μM), phototreatment and filtration (C). Biochemical and coagulation tests were performed; units A and B were reinfused. Results: Filtration reduced MB to undetectable (
ISSN:	0042-9007 1423-0410
DOI:	10.1046/j.1423-0410.1998.7410001.x