Improvement in blood flow and diameter of the postanastomotic rat tail artery by topical application of lidocaine in varying concentrations

Prolonged spasm in small vessels is a major problem after microsurgical procedures. Topical agents applied to resolve these spasms have been the subject of many experimental studies. In this model we studied the effectiveness of various concentrations of lidocaine in resolving microvascular spasms i...

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Veröffentlicht in:	Annals of plastic surgery 1990-03, Vol.24 (3), p.248-251
Hauptverfasser:	BEEKMAN, W. H, DAMMEIJER, P. F, SLUIMERS, J. E, KORT, W. J, VAN DER MEULEN, J. H. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Anastomosis, Surgical Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Lidocaine - administration & dosage Lidocaine - pharmacology Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Postoperative Period Random Allocation Rats Rats, Inbred BN Regional Blood Flow - drug effects Tail - anatomy & histology Tail - blood supply Tail - surgery Vascular Patency - drug effects
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Beschreibung
Zusammenfassung:	Prolonged spasm in small vessels is a major problem after microsurgical procedures. Topical agents applied to resolve these spasms have been the subject of many experimental studies. In this model we studied the effectiveness of various concentrations of lidocaine in resolving microvascular spasms induced by anastomosing the ventral rat tail artery.
ISSN:	0148-7043 1536-3708
DOI:	10.1097/00000637-199003000-00009