Age-related changes in rat liver phospholipid transfer activity
The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regr...
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| Veröffentlicht in: | Experimental gerontology 1990, Vol.25 (1), p.55-60 |
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| container_title | Experimental gerontology |
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| creator | Markovska, Tania T. Petkova, Diana H. Momchilova-Pankova, A.B. Koumanov, K.S. |
| description | The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats. |
| doi_str_mv | 10.1016/0531-5565(90)90009-Q |
| format | Article |
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These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.</description><identifier>ISSN: 0531-5565</identifier><identifier>EISSN: 1873-6815</identifier><identifier>DOI: 10.1016/0531-5565(90)90009-Q</identifier><identifier>PMID: 2318282</identifier><identifier>CODEN: EXGEAB</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>aging ; Aging - metabolism ; Animals ; Biological and medical sciences ; Carrier Proteins - metabolism ; Cytosol - metabolism ; Female ; Fundamental and applied biological sciences. Psychology ; Liver - cytology ; Liver - metabolism ; Liver. Bile. Biliary tracts ; Male ; Membrane Lipids - metabolism ; phosphatidylcholine ; Phosphatidylcholines - metabolism ; phosphatidylethanolamine ; Phosphatidylethanolamines - metabolism ; phospholipid transfer activity ; Phospholipids - metabolism ; Rats ; Rats, Inbred Strains ; Vertebrates: digestive system</subject><ispartof>Experimental gerontology, 1990, Vol.25 (1), p.55-60</ispartof><rights>1990</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-22ce9882c2b613c52cd561030e94528298146999e500bba7196a2772fc50ba23</citedby><cites>FETCH-LOGICAL-c416t-22ce9882c2b613c52cd561030e94528298146999e500bba7196a2772fc50ba23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0531-5565(90)90009-Q$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19726854$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2318282$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Markovska, Tania T.</creatorcontrib><creatorcontrib>Petkova, Diana H.</creatorcontrib><creatorcontrib>Momchilova-Pankova, A.B.</creatorcontrib><creatorcontrib>Koumanov, K.S.</creatorcontrib><title>Age-related changes in rat liver phospholipid transfer activity</title><title>Experimental gerontology</title><addtitle>Exp Gerontol</addtitle><description>The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.</description><subject>aging</subject><subject>Aging - metabolism</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carrier Proteins - metabolism</subject><subject>Cytosol - metabolism</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Liver - cytology</subject><subject>Liver - metabolism</subject><subject>Liver. Bile. Biliary tracts</subject><subject>Male</subject><subject>Membrane Lipids - metabolism</subject><subject>phosphatidylcholine</subject><subject>Phosphatidylcholines - metabolism</subject><subject>phosphatidylethanolamine</subject><subject>Phosphatidylethanolamines - metabolism</subject><subject>phospholipid transfer activity</subject><subject>Phospholipids - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Vertebrates: digestive system</subject><issn>0531-5565</issn><issn>1873-6815</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotX78A4W9KHpYTbKbbHJRSvELClLoPWSzs21ku7smaaH_3tSWevMwGcg88zI8CF0R_EAw4Y-YZSRljLM7ie8lxlim0yM0JKLIUi4IO0bDA3KKzrz_igynGRmgQXwFFXSInkdzSB00OkCVmIVu5-AT2yZOh6Sxa3BJv-h8rMb2tkqC062v4682wa5t2Fygk1o3Hi73_RzNXl9m4_d08vn2MR5NUpMTHlJKDUghqKElJ5lh1FSME5xhkDmLh0hBci6lBIZxWeqCSK5pUdDaMFxqmp2j211s77rvFfigltYbaBrdQrfyqpBcCCZ5BPMdaFznvYNa9c4utdsogtVWm9o6UVsnSmL1q01N49r1Pn9VLqE6LO09xfnNfq690U0dNRjr_7JlQblgeeSedhxEF2sLTnljoTVQWQcmqKqz_x_yA0zth44</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Markovska, Tania T.</creator><creator>Petkova, Diana H.</creator><creator>Momchilova-Pankova, A.B.</creator><creator>Koumanov, K.S.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Age-related changes in rat liver phospholipid transfer activity</title><author>Markovska, Tania T. ; Petkova, Diana H. ; Momchilova-Pankova, A.B. ; Koumanov, K.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-22ce9882c2b613c52cd561030e94528298146999e500bba7196a2772fc50ba23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>aging</topic><topic>Aging - metabolism</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carrier Proteins - metabolism</topic><topic>Cytosol - metabolism</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Liver - cytology</topic><topic>Liver - metabolism</topic><topic>Liver. Bile. Biliary tracts</topic><topic>Male</topic><topic>Membrane Lipids - metabolism</topic><topic>phosphatidylcholine</topic><topic>Phosphatidylcholines - metabolism</topic><topic>phosphatidylethanolamine</topic><topic>Phosphatidylethanolamines - metabolism</topic><topic>phospholipid transfer activity</topic><topic>Phospholipids - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Vertebrates: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Markovska, Tania T.</creatorcontrib><creatorcontrib>Petkova, Diana H.</creatorcontrib><creatorcontrib>Momchilova-Pankova, A.B.</creatorcontrib><creatorcontrib>Koumanov, K.S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental gerontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Markovska, Tania T.</au><au>Petkova, Diana H.</au><au>Momchilova-Pankova, A.B.</au><au>Koumanov, K.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age-related changes in rat liver phospholipid transfer activity</atitle><jtitle>Experimental gerontology</jtitle><addtitle>Exp Gerontol</addtitle><date>1990</date><risdate>1990</risdate><volume>25</volume><issue>1</issue><spage>55</spage><epage>60</epage><pages>55-60</pages><issn>0531-5565</issn><eissn>1873-6815</eissn><coden>EXGEAB</coden><abstract>The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>2318282</pmid><doi>10.1016/0531-5565(90)90009-Q</doi><tpages>6</tpages></addata></record> |
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| ispartof | Experimental gerontology, 1990, Vol.25 (1), p.55-60 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Freedom Collection (Elsevier) |
| subjects | aging Aging - metabolism Animals Biological and medical sciences Carrier Proteins - metabolism Cytosol - metabolism Female Fundamental and applied biological sciences. Psychology Liver - cytology Liver - metabolism Liver. Bile. Biliary tracts Male Membrane Lipids - metabolism phosphatidylcholine Phosphatidylcholines - metabolism phosphatidylethanolamine Phosphatidylethanolamines - metabolism phospholipid transfer activity Phospholipids - metabolism Rats Rats, Inbred Strains Vertebrates: digestive system |
| title | Age-related changes in rat liver phospholipid transfer activity |
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