Age-related changes in rat liver phospholipid transfer activity

The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regr...

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Veröffentlicht in:	Experimental gerontology 1990, Vol.25 (1), p.55-60
Hauptverfasser:	Markovska, Tania T., Petkova, Diana H., Momchilova-Pankova, A.B., Koumanov, K.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	aging Aging - metabolism Animals Biological and medical sciences Carrier Proteins - metabolism Cytosol - metabolism Female Fundamental and applied biological sciences. Psychology Liver - cytology Liver - metabolism Liver. Bile. Biliary tracts Male Membrane Lipids - metabolism phosphatidylcholine Phosphatidylcholines - metabolism phosphatidylethanolamine Phosphatidylethanolamines - metabolism phospholipid transfer activity Phospholipids - metabolism Rats Rats, Inbred Strains Vertebrates: digestive system
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Beschreibung
Zusammenfassung:	The age-induced changes in the liver cytosol phospholipid transfer activity of male and female rats have been investigated. These changes were found to be closely related to the age-induced alterations in the two major microsomal phospholipids — phosphatidylcholine and phosphatidylethanolamine. Regression analysis indicated a linear correlation between the phospholipid transfer activity and the level of phosphatidylcholine (positive) and phosphatidylethanolamine (negative) in liver microsomes of both male and female rats.
ISSN:	0531-5565 1873-6815
DOI:	10.1016/0531-5565(90)90009-Q