Collagen and Elastin Metabolism in Hypertensive Pulmonary Arteries of Rats

We evaluated the processes controlling the accumulation of collagen and elastin in main pulmonary arteries of rats during an episode of hypoxic pulmonary hypertension. Explant cultures of main pulmonary arteries were incubated with [H]proline to measure collagen and protein synthesis and percent col...

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Veröffentlicht in:	Circulation research 1990-04, Vol.66 (4), p.968-978
Hauptverfasser:	Poiani, George J, Tozzi, Carol A, Yohn, Susan E, Pierce, Richard A, Belsky, Sandra A, Berg, Richard A, Yu, Shiu Y, Deak, Susan B, Riley, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Animals Biological and medical sciences Cardiology. Vascular system Chronic cor pulmonale Collagen - metabolism Elastin - metabolism Heart Hypertension - metabolism Hypertension - physiopathology Medical sciences Pneumology Procollagen - genetics Proteins - metabolism Pulmonary Artery - metabolism Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Rats Rats, Inbred Strains RNA, Messenger - metabolism
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