Minimal residual disease analysis for the prediction of relapse in children with standard‐risk acute lymphoblastic leukaemia

We report a largely retrospective analysis of minimal residual disease (MRD) in a cohort of 66 children suffering from acute lymphoblastic leukaemia (ALL). All patients lacked high‐risk features at diagnosis, i.e. the presenting white cell count was

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Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 1998-01, Vol.100 (1), p.235-244
Hauptverfasser:	Goulden, Nicholas J., Knechtli, Christopher J. C., Garland, Russell J., Langlands, Kenneth, Hancock, Jeremy P., Potter, Michael N., Steward, Colin G., Oakhill, Anthony
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lymphoblastic leukaemia Adolescent Adult Base Sequence Biological and medical sciences Child Child, Preschool Cohort Studies Female Forecasting Gene Rearrangement Hematologic and hematopoietic diseases Humans immunoglobulin heavy chain gene Infant Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences minimal residual disease Molecular Sequence Data Neoplasm, Residual Polymerase Chain Reaction Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Recurrence Retrospective Studies risk factor Risk Factors Sensitivity and Specificity T‐cell receptor gene
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Beschreibung
Zusammenfassung:	We report a largely retrospective analysis of minimal residual disease (MRD) in a cohort of 66 children suffering from acute lymphoblastic leukaemia (ALL). All patients lacked high‐risk features at diagnosis, i.e. the presenting white cell count was
ISSN:	0007-1048 1365-2141
DOI:	10.1046/j.1365-2141.1998.00574.x