Factor V Leiden Mutation in a Case with Ischemic Stroke: which Relationship?: A Case Report

A 50-year-old man presented spontaneous internal carotid artery dissection with ischemic stroke. He had a history of deep venous thrombosis, and an activated protein C resistance due to factor V Leiden mutation was documented. He showed no other vascular risk factor. This unusual case puts the quest...

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Veröffentlicht in:	Angiology 1998-01, Vol.49 (1), p.79-82
Hauptverfasser:	Orlandi, Giovanni, Pellegrinetti, Alberto, Fioretti, Cristina, Martini, Antonio, Murri, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneurysm, Dissecting - etiology Anticoagulants - therapeutic use Biological and medical sciences Brain Ischemia - etiology Carotid Artery, Internal Carotid Stenosis - etiology Cerebrovascular Disorders - etiology Factor V - genetics Follow-Up Studies Heparin - therapeutic use Humans Male Medical sciences Middle Aged Neurology Point Mutation - genetics Protein C Thrombophlebitis - drug therapy Thrombophlebitis - etiology Vascular diseases and vascular malformations of the nervous system Warfarin - therapeutic use
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Zusammenfassung:	A 50-year-old man presented spontaneous internal carotid artery dissection with ischemic stroke. He had a history of deep venous thrombosis, and an activated protein C resistance due to factor V Leiden mutation was documented. He showed no other vascular risk factor. This unusual case puts the question whether this coagulation defect may be related to the stroke occurrence.
ISSN:	0003-3197 1940-1574
DOI:	10.1177/000331979804900111