Secretion: Dense-core vesicles can kiss-and-run too

Secretion: Dense-core vesicles can kiss-and-run too

New measurements show that the entire transmitter contents of a dense-core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense core vesicles may, like small synaptic vesicles, undergo immediate r...

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Veröffentlicht in:Current biology 1998-01, Vol.8 (2), p.R62-R65
Hauptverfasser: Artalejo, Cristina R, Elhamdani, Abdeladim, Palfrey, H.Clive
Format: Artikel
Sprache:eng
Schlagworte:
Catecholamines - metabolism
Cell Degranulation
Exocytosis - physiology
Models, Biological
Neurotransmitter Agents - metabolism
Organelles - metabolism
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Zusammenfassung:New measurements show that the entire transmitter contents of a dense-core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense core vesicles may, like small synaptic vesicles, undergo immediate recycling.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(98)70036-3