CEREBROSPINAL FLUID CONCENTRATIONS OF LAUDANOSINE AFTER ADMINISTRATION OF ATRACURIUM

CEREBROSPINAL FLUID CONCENTRATIONS OF LAUDANOSINE AFTER ADMINISTRATION OF ATRACURIUM

The concentration of laudanosine in cerebro-spinal fluid (CSF) was measured in four patients undergoing brain electrode placement after the administration of atracurium. CSF: plasma laudanosine concentration ratios ranged from < 1 to 14%, with a range of CSF laudanosine concentration of

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Bibliographische Detailangaben
Veröffentlicht in:British journal of anaesthesia : BJA 1990-01, Vol.64 (1), p.105-106
Hauptverfasser: FAHEY, M.R., CANFELL, P. CLAVER, TABOADA, T., HOSOBUCHI, Y., MILLER, R.D.
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia, General
Anesthetics. Neuromuscular blocking agents
Atracurium - pharmacokinetics
Biological and medical sciences
Blood-Brain Barrier
Cerebrospinal fluid: laudanosine
Humans
Isoquinolines - cerebrospinal fluid
Medical sciences
Neuromuscular relaxants: atracurium
Neuropharmacology
Opium - cerebrospinal fluid
Pharmacokinetics: laudanosine
Pharmacology. Drug treatments
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Zusammenfassung:The concentration of laudanosine in cerebro-spinal fluid (CSF) was measured in four patients undergoing brain electrode placement after the administration of atracurium. CSF: plasma laudanosine concentration ratios ranged from < 1 to 14%, with a range of CSF laudanosine concentration of
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/64.1.105