The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia
The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had bee...
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| Veröffentlicht in: | Genomics (San Diego, Calif.) Calif.), 1990, Vol.6 (1), p.144-148 |
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| container_title | Genomics (San Diego, Calif.) |
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| creator | Sutherland, Grant R. Baker, Elizabeth Callen, David F. Garson, O.Margaret West, Adrian K. |
| description | The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution
in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had been previously reported. The locus order on 16q is cen-
MT-FRA16B-D16S4-inversion breakpoint-
HP-tel. |
| doi_str_mv | 10.1016/0888-7543(90)90459-8 |
| format | Article |
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in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had been previously reported. The locus order on 16q is cen-
MT-FRA16B-D16S4-inversion breakpoint-
HP-tel.</description><identifier>ISSN: 0888-7543</identifier><identifier>EISSN: 1089-8646</identifier><identifier>DOI: 10.1016/0888-7543(90)90459-8</identifier><identifier>PMID: 2303255</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Blotting, Southern ; Chromosome Banding ; Chromosomes, Human, Pair 16 ; DNA - analysis ; DNA Probes ; genes ; Humans ; Leukemia, Myelomonocytic, Acute - genetics ; Metallothionein - genetics ; myelomonocytic leukemia ; Nucleic Acid Hybridization</subject><ispartof>Genomics (San Diego, Calif.), 1990, Vol.6 (1), p.144-148</ispartof><rights>1990</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-8dc57e20e79f55aaaeccf25ca43f9120dfbbd014a1fc546f35b3b4471428e1c3</citedby><cites>FETCH-LOGICAL-c388t-8dc57e20e79f55aaaeccf25ca43f9120dfbbd014a1fc546f35b3b4471428e1c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0888754390904598$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2303255$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sutherland, Grant R.</creatorcontrib><creatorcontrib>Baker, Elizabeth</creatorcontrib><creatorcontrib>Callen, David F.</creatorcontrib><creatorcontrib>Garson, O.Margaret</creatorcontrib><creatorcontrib>West, Adrian K.</creatorcontrib><title>The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia</title><title>Genomics (San Diego, Calif.)</title><addtitle>Genomics</addtitle><description>The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution
in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had been previously reported. The locus order on 16q is cen-
MT-FRA16B-D16S4-inversion breakpoint-
HP-tel.</description><subject>Blotting, Southern</subject><subject>Chromosome Banding</subject><subject>Chromosomes, Human, Pair 16</subject><subject>DNA - analysis</subject><subject>DNA Probes</subject><subject>genes</subject><subject>Humans</subject><subject>Leukemia, Myelomonocytic, Acute - genetics</subject><subject>Metallothionein - genetics</subject><subject>myelomonocytic leukemia</subject><subject>Nucleic Acid Hybridization</subject><issn>0888-7543</issn><issn>1089-8646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMo67r6DxRyEj1UkyZpk4sg4hcIguw9pOnUjbbNmqTC_nu77rJHPc3APO878CB0SskVJbS4JlLKrBScXShyqQgXKpN7aEqJHJeCF_toukMO0VGMH4QQxWQ-QZOcEZYLMUVv8wXgxdCZHneQTNv6tHC-B9fjd-gB23aICQJ2Efc-4drFMCwT1HgEuhW0vvO9t6vkLG5h-ITOmWN00Jg2wsl2ztD84X5-95S9vD4-392-ZJZJmTJZW1FCTqBUjRDGGLC2yYU1nDWK5qRuqqomlBvaWMGLhomKVZyXlOcSqGUzdL6pXQb_NUBMunPRQtuaHvwQdakKWihZ_gtSwRTjTI4g34A2-BgDNHoZXGfCSlOi18r12qde-9SK6F_leh072_YPVQf1LrR1PN5vNncYZXw7CDpaB72F2gWwSdfe_f3gB-kFkck</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Sutherland, Grant R.</creator><creator>Baker, Elizabeth</creator><creator>Callen, David F.</creator><creator>Garson, O.Margaret</creator><creator>West, Adrian K.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T3</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia</title><author>Sutherland, Grant R. ; Baker, Elizabeth ; Callen, David F. ; Garson, O.Margaret ; West, Adrian K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-8dc57e20e79f55aaaeccf25ca43f9120dfbbd014a1fc546f35b3b4471428e1c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Blotting, Southern</topic><topic>Chromosome Banding</topic><topic>Chromosomes, Human, Pair 16</topic><topic>DNA - analysis</topic><topic>DNA Probes</topic><topic>genes</topic><topic>Humans</topic><topic>Leukemia, Myelomonocytic, Acute - genetics</topic><topic>Metallothionein - genetics</topic><topic>myelomonocytic leukemia</topic><topic>Nucleic Acid Hybridization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sutherland, Grant R.</creatorcontrib><creatorcontrib>Baker, Elizabeth</creatorcontrib><creatorcontrib>Callen, David F.</creatorcontrib><creatorcontrib>Garson, O.Margaret</creatorcontrib><creatorcontrib>West, Adrian K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Human Genome Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Genomics (San Diego, Calif.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sutherland, Grant R.</au><au>Baker, Elizabeth</au><au>Callen, David F.</au><au>Garson, O.Margaret</au><au>West, Adrian K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia</atitle><jtitle>Genomics (San Diego, Calif.)</jtitle><addtitle>Genomics</addtitle><date>1990</date><risdate>1990</risdate><volume>6</volume><issue>1</issue><spage>144</spage><epage>148</epage><pages>144-148</pages><issn>0888-7543</issn><eissn>1089-8646</eissn><abstract>The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution
in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had been previously reported. The locus order on 16q is cen-
MT-FRA16B-D16S4-inversion breakpoint-
HP-tel.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>2303255</pmid><doi>10.1016/0888-7543(90)90459-8</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0888-7543 |
| ispartof | Genomics (San Diego, Calif.), 1990, Vol.6 (1), p.144-148 |
| issn | 0888-7543 1089-8646 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79616987 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Blotting, Southern Chromosome Banding Chromosomes, Human, Pair 16 DNA - analysis DNA Probes genes Humans Leukemia, Myelomonocytic, Acute - genetics Metallothionein - genetics myelomonocytic leukemia Nucleic Acid Hybridization |
| title | The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia |
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