The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia

The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia

The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had bee...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genomics (San Diego, Calif.) Calif.), 1990, Vol.6 (1), p.144-148
Hauptverfasser: Sutherland, Grant R., Baker, Elizabeth, Callen, David F., Garson, O.Margaret, West, Adrian K.
Format: Artikel
Sprache:eng
Schlagworte:
Blotting, Southern
Chromosome Banding
Chromosomes, Human, Pair 16
DNA - analysis
DNA Probes
genes
Humans
Leukemia, Myelomonocytic, Acute - genetics
Metallothionein - genetics
myelomonocytic leukemia
Nucleic Acid Hybridization
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The human metallothionein gene complex on chromosome 16 has been remapped to 16q13 using high-resolution in situ hybridization. The complex is not disrupted by the rearrangement breakpoint on the long arm of chromosome 16 in patients with myelomonocytic leukemia with abnormal eosinophils, as had been previously reported. The locus order on 16q is cen- MT-FRA16B-D16S4-inversion breakpoint- HP-tel.
ISSN:0888-7543
1089-8646
DOI:10.1016/0888-7543(90)90459-8