Children born after their fathers had been treated with chemotherapy for testicular cancer

Twenty children fathered by 15 patients treated with platinum-based combination chemotherapy for disseminated testicular carcinoma were examined and found to have no evidence of congenital malformations. The results indicate no reason for advising against pregnancies in this group of young couples.

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of obstetrics & gynecology and reproductive biology 1990, Vol.34 (1), p.167-170
Hauptverfasser:	van der Kolk, B.M., Mulder, N.H., Mantingh, A., van den Berg, E., Koops, H.Schraffordt, de Vries, E.G.E., Willemse, P.H.B., Sleijfer, D.Th
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bleomycin - therapeutic use Chemotherapy Cisplatin - therapeutic use Drug toxicity and drugs side effects treatment Female Humans Male Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Offspring Pharmacology. Drug treatments Pregnancy Pregnancy Outcome Testicular cancer Testicular Neoplasms - drug therapy Vinblastine - therapeutic use
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Beschreibung
Zusammenfassung:	Twenty children fathered by 15 patients treated with platinum-based combination chemotherapy for disseminated testicular carcinoma were examined and found to have no evidence of congenital malformations. The results indicate no reason for advising against pregnancies in this group of young couples.
ISSN:	0301-2115 1872-7654
DOI:	10.1016/0028-2243(90)90020-2