Quantitative MRI in Outpatient Childhood Epilepsy

Quantitative MRI in Outpatient Childhood Epilepsy

Purpose: In adult studies, MRI volumetrics is a proven technique in presurgical assessment of epilepsy. Hippocampal volume loss is maximal in the syndrome of mesial temporal lobe epilepsy. We aimed (a) to validate this methodology in a pediatric outpatient epilepsy population (b) to determine the re...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Epilepsia (Copenhagen) 1997-12, Vol.38 (12), p.1289-1293
Hauptverfasser: Lawson, John A., Cook, Mark J., Bleasel, Andrew F., Nayanar, Vimala, Morris, Kevin F., Bye, Ann M. E.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age Factors
Age of Onset
Aged
Ambulatory Care
Biological and medical sciences
Child
Child, Preschool
Childhood
Comorbidity
Electroencephalography
Epilepsy
Epilepsy - classification
Epilepsy - diagnosis
Epilepsy - epidemiology
Family
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Hippocampus
Hippocampus - anatomy & histology
Humans
Infant
Intellectual Disability - diagnosis
Intellectual Disability - epidemiology
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
MRI
Nervous system (semeiology, syndromes)
Neurology
Risk Factors
Seizures, Febrile - diagnosis
Seizures, Febrile - epidemiology
Syndrome
Tropical medicine
Volumetrics
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Purpose: In adult studies, MRI volumetrics is a proven technique in presurgical assessment of epilepsy. Hippocampal volume loss is maximal in the syndrome of mesial temporal lobe epilepsy. We aimed (a) to validate this methodology in a pediatric outpatient epilepsy population (b) to determine the relationship of hippocampal asymmetry (HA) to epileptic syndromes and risk factors. Methods: Two neurologists classified the epileptic syndrome in 79 pediatric outpatients, according to the International Classification of Epilepsies and Epileptic Syndromes (ILAE). Hippocampal volumetrics were performed in all patients. HA was defined according to adult control values. Results: Inter‐rater variability on measurement of HA was very small (Correlation of test retest of 0.97 on 17 children
ISSN:0013-9580
1528-1167
DOI:10.1111/j.1528-1157.1997.tb00066.x