Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

Interleukins (IL)-1β and -1α and tumor necrosis factor (TNF-α) were measured by radioimmunoassay in plasma samples from 44 healthy individuals, 15 patients in septic shock, and 6 volunteers infused with endotoxin. Plasma IL-1α levels were low (40 pg/ml) or undetectable in all situations. In 67% ofth...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 1990-01, Vol.161 (1), p.79-84
Hauptverfasser:	Cannon, Joseph G., Tompkins, Ronald G., Gelfand, Jeffrey A., Michie, Hamish R., Stanford, Gregory G., van der Meer, Jos W. M., Endres, Stefan, Lonnemann, Gerhard, Corsetti, John, Chernow, Bart, Wilmore, Douglas W., Wolff, Sheldon M., Burke, John F., Dinarello, Charles A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Bacterial diseases Biological and medical sciences Blood Blood plasma Cytokines Diseases Endotoxins Endotoxins - administration & dosage Female Fever Fever - blood Fever - chemically induced General aspects Humans Infectious diseases Interleukin-1 - blood Leukocytes Major Articles Male Medical sciences Middle Aged Radioimmunoassay Sepsis Septic shock Shock, Septic - blood Shock, Septic - mortality Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Interleukins (IL)-1β and -1α and tumor necrosis factor (TNF-α) were measured by radioimmunoassay in plasma samples from 44 healthy individuals, 15 patients in septic shock, and 6 volunteers infused with endotoxin. Plasma IL-1α levels were low (40 pg/ml) or undetectable in all situations. In 67% ofthe healthy subjects, plasma IL-1β levels were
ISSN:	0022-1899 1537-6613
DOI:	10.1093/infdis/161.1.79