Palladium(II)-coproporphyrin I as a photoactivable group in sequence-specific modification of nucleic acids by oligonucleotide derivatives

The 34-mer oligodeoxynucleotide was shown to be selectively modified at the G17 position upon photoirradiation in the presence of complementary 17-mer oligodeoxynucleotide bearing Pd(II)-coproporphyrin I covalently linked to the 5'-end phosphate group.

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Veröffentlicht in:FEBS letters 1990, Vol.259 (2), p.335-337
Hauptverfasser: Fedorova, O.S., Savitskii, A.P., Shoikhet, K.G., Ponomarev, G.V.
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container_end_page 337
container_issue 2
container_start_page 335
container_title FEBS letters
container_volume 259
creator Fedorova, O.S.
Savitskii, A.P.
Shoikhet, K.G.
Ponomarev, G.V.
description The 34-mer oligodeoxynucleotide was shown to be selectively modified at the G17 position upon photoirradiation in the presence of complementary 17-mer oligodeoxynucleotide bearing Pd(II)-coproporphyrin I covalently linked to the 5'-end phosphate group.
doi_str_mv 10.1016/0014-5793(90)80041-G
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Analytical, structural and metabolic biochemistry
Autoradiography
Base Sequence
Biological and medical sciences
CMC, N-cyclohexyl-N'-morpholinoethyl carbodiimide metho-p-toluenesulfonate
Coproporphyrins
DMAP, 4-dimethylaminopyridine
DMF, dimethylformamide
DMSO, dimethylsulfoxide
Fundamental and applied biological sciences. Psychology
Molecular Sequence Data
Nucleic acids
Nucleic bases, nucleotides
Oligodeoxyribonucleotides - chemical synthesis
Palladium
Pd(II)-coproporphyrin I
Phosphorus Radioisotopes
Photochemistry
Photoirradiation
Por (COOH)4, palladium (II)-coproporphyrin I
Porphyrins
Sequence-specific modification
title Palladium(II)-coproporphyrin I as a photoactivable group in sequence-specific modification of nucleic acids by oligonucleotide derivatives
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