Minimum effective doses of mebendazole in treatment of soil-transmitted helminths

Three hundred and fifteen primary school children infected with soil-transmitted helminths were divided into 5 groups. Three groups were treated with 25, 50 and 75 mg mebendazole (MBZ) single dose. One group was given MBZ conventional dose of 100 mg twice daily for 3 days and another group was given...

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Veröffentlicht in:	Southeast Asian journal of tropical medicine and public health 1997-06, Vol.28 (2), p.326-328
Hauptverfasser:	NONTASUT, P, WAIKAGUL, J, MUENNOO, C, SANGUANKAIT, S, NUAMTANONG, S, MAIPANICH, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antinematodal Agents - administration & dosage Antiparasitic agents Ascariasis - drug therapy Ascaris lumbricoides Biological and medical sciences Child Dosage Forms Humans Mebendazole - administration & dosage Medical sciences Necatoriasis - drug therapy Pharmacology. Drug treatments Thailand Trichuriasis - drug therapy Tropical medicine
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Zusammenfassung:	Three hundred and fifteen primary school children infected with soil-transmitted helminths were divided into 5 groups. Three groups were treated with 25, 50 and 75 mg mebendazole (MBZ) single dose. One group was given MBZ conventional dose of 100 mg twice daily for 3 days and another group was given albendazole (ABZ) standard dose of 400 mg single dose. Every trial lower MBZ dose 75 mg, 50 mg and 25 mg regimen were highly effective against Ascaris lumbricoides but only moderately effective against Trichuris trichiura and Necator americanus.
ISSN:	0125-1562