Systemic absorption of gentamicin ear drops
Aminoglycoside-containing topical preparations are commonly used in the treatment of chronic suppurative otitis media and otitis externa. We report a case where systemic absorption of topical Gentisone HC™ occurred producing a serum gentamicin level of 6.2 μg/ml.
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| Veröffentlicht in: | Journal of laryngology and otology 1997-10, Vol.111 (10), p.960-962 |
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| container_end_page | 962 |
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| container_issue | 10 |
| container_start_page | 960 |
| container_title | Journal of laryngology and otology |
| container_volume | 111 |
| creator | Green, K. M. J. Lappin, D. W. P. Curley, J. W. A. de Carpentier, J. P. |
| description | Aminoglycoside-containing topical preparations are commonly used in the treatment of chronic suppurative otitis media and otitis externa. We report a case where systemic absorption of topical Gentisone HC™ occurred producing a serum gentamicin level of 6.2 μg/ml. |
| doi_str_mv | 10.1017/S0022215100139076 |
| format | Article |
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We report a case where systemic absorption of topical Gentisone HC™ occurred producing a serum gentamicin level of 6.2 μg/ml.</description><subject>Absorption</subject><subject>Administration, Topical</subject><subject>Anti-Bacterial Agents - blood</subject><subject>Anti-Bacterial Agents - pharmacokinetics</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Clinical Records</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Ear</subject><subject>Gentamicin</subject><subject>Gentamicins - blood</subject><subject>Gentamicins - pharmacokinetics</subject><subject>Gentamicins - therapeutic use</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Otitis Media, Suppurative - blood</subject><subject>Otitis Media, Suppurative - drug therapy</subject><subject>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0022-2151 |
| ispartof | Journal of laryngology and otology, 1997-10, Vol.111 (10), p.960-962 |
| issn | 0022-2151 1748-5460 1748-5640 |
| language | eng |
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| source | MEDLINE; Cambridge University Press Journals Complete |
| subjects | Absorption Administration, Topical Anti-Bacterial Agents - blood Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - therapeutic use Biological and medical sciences Clinical Records Drug toxicity and drugs side effects treatment Ear Gentamicin Gentamicins - blood Gentamicins - pharmacokinetics Gentamicins - therapeutic use Humans Kidney Failure, Chronic - blood Male Medical sciences Middle Aged Otitis Media, Suppurative - blood Otitis Media, Suppurative - drug therapy Pharmacology. Drug treatments toxicity Toxicity: blood |
| title | Systemic absorption of gentamicin ear drops |
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