Expression of natural peptide antibiotics in human skin

Fulton et al investigated the expression of human beta defensin 1 (HBD1) in normal human skin by RT-PCR and in-situ hybridization to determine if this gene is expressed and the distribution of transcripts within the epidermis.

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Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 1997-12, Vol.350 (9093), p.1750-1751
Hauptverfasser:	Fulton, Clare, Anderson, G Mark, Zasloff, Michael, Bull, Richard, Quinn, Anthony G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - analysis Antibiotics Biological and medical sciences Blood Proteins - analysis Blood Proteins - genetics Defensins Epidermis Fundamental and applied biological sciences. Psychology Genes Humans In Situ Hybridization Keratinocytes - chemistry Peptides Polymerase Chain Reaction Skin Skin - chemistry Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue
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Beschreibung
Zusammenfassung:	Fulton et al investigated the expression of human beta defensin 1 (HBD1) in normal human skin by RT-PCR and in-situ hybridization to determine if this gene is expressed and the distribution of transcripts within the epidermis.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(05)63574-X