Calcium and sodium transport in gestational hypertension

The enzymatic activities of Na +/K + ATPase and Ca 2+ ATPase were determined on erythrocyte membranes from 9 normotensive and 9 gestational hypertensive pregnant women near term. A reduction in the activity of the Na +/K + ATPase and a relative increase in the activity of the Ca 2+ ATPase were found...

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Veröffentlicht in:International journal of cardiology 1989, Vol.25, p.S53-S55
Hauptverfasser: Tranquilli, Andrea Luigi, Rabini, Rosa Anna, Cugini, Anna Maria, Cester, Nelvio, Valensise, Herbert, Romanini, Carlo, Bertoli, Enrico, Mazzanti, Laura
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Sprache:eng
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Zusammenfassung:The enzymatic activities of Na +/K + ATPase and Ca 2+ ATPase were determined on erythrocyte membranes from 9 normotensive and 9 gestational hypertensive pregnant women near term. A reduction in the activity of the Na +/K + ATPase and a relative increase in the activity of the Ca 2+ ATPase were found in the hypertensive patients, possibly due to a conformational alteration of erythrocyte membranes. This observation supports the possible role of the transmembrane cation transport in the pathogenesis of gestational hypertension.
ISSN:0167-5273
1874-1754
DOI:10.1016/0167-5273(89)90093-4