Goniotriol from Goniothalamus giganteus

The known styrylpyrone, goniotriol, has been isolated from Goniothalamus giganteus. Its bioactivities are reported, and its structure and relative stereochemistry have been determined by X-ray crystallography as 6R-(7R,8R-dihydro-7,8-dihydroxystyryl)-5S,6R-dihydro-5-hydroxy-2-p yrone.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1989-11, Vol.52 (6), p.1371-1373
Hauptverfasser:	Alkofahi, A. (Jordan University of Science and Technology, Irbid, Jordan), Ma, W.W, McKenzie, A.T, Byrn, S.R, McLaughlin, J.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ANNONACEAE Antineoplastic Agents, Phytogenic - isolation & purification Artemia - drug effects Biological and medical sciences COMPOSICION COMPOSITION CRYSTALLOGRAPHY Drug Screening Assays, Antitumor General pharmacology Humans Medical sciences MINERALOGIA MINERALOGIE MINERALOGY Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plants - analysis Pyrans - isolation & purification Pyrones - isolation & purification Pyrones - pharmacology Tumor Cells, Cultured
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Beschreibung
Zusammenfassung:	The known styrylpyrone, goniotriol, has been isolated from Goniothalamus giganteus. Its bioactivities are reported, and its structure and relative stereochemistry have been determined by X-ray crystallography as 6R-(7R,8R-dihydro-7,8-dihydroxystyryl)-5S,6R-dihydro-5-hydroxy-2-p yrone.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50066a037