Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin

Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin

Lomefloxacin was found to be comparable to ciprofloxacin in its ability to inhibit the in vitro growth of Mycoplasma pneumoniae (MIC range 2–8 mcg/ml), but it was significantly less active than erythromycin. Although 30 different strains from widely differing geographic areas and isolation time peri...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 1989-09, Vol.12 (5), p.433-435
Hauptverfasser: Cassell, G.H., Waites, K.B., Pate, M.S., Canupp, K.C., Duffy, L.B.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Infective Agents - pharmacology
Antibiotics (antibacterial agents, antifungal agents)
Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents
Applied microbiology
Biological and medical sciences
Ciprofloxacin - pharmacology
Erythromycin - pharmacology
Fluoroquinolones
Fundamental and applied biological sciences. Psychology
Humans
Microbiology
Mycoplasma pneumoniae - drug effects
Quinolones
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Zusammenfassung:Lomefloxacin was found to be comparable to ciprofloxacin in its ability to inhibit the in vitro growth of Mycoplasma pneumoniae (MIC range 2–8 mcg/ml), but it was significantly less active than erythromycin. Although 30 different strains from widely differing geographic areas and isolation time periods were examined, no macrolide-resistant strains were observed.
ISSN:0732-8893
1879-0070
DOI:10.1016/0732-8893(89)90115-6