Time course of serum amyloid A response in myocardial infarction

Plasma concentrations of serum amyloid A (SAA), high density lipoprotein (HDL) cholesterol, non-HDL cholesterol, and apolipoproteins (Apo) A-I and B were measured daily for 6 days in 10 patients following myocardial infarction (MI) and in 10 secular controls admitted to a coronary care unit. SAA con...

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Veröffentlicht in:	Clinica chimica acta 1989-10, Vol.184 (3), p.297-305
Hauptverfasser:	Bausserman, Linda L., Sadaniantz, Ara, Saritelli, Ann L., Martin, Virginia L., Nugent, Anne M., Sady, Stanley P., Herbert, Peter N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute phase response Adult Aged Aged, 80 and over Apolipoprotein A-I Apolipoproteins A - blood Apolipoproteins B - blood Biological and medical sciences Cardiology. Vascular system Cholesterol - blood Cholesterol, HDL - blood Coronary heart disease Female Heart Humans Lipoprotein Male Medical sciences Middle Aged Myocardial infarction Myocardial Infarction - blood Serum amyloid A Serum Amyloid A Protein - metabolism Time Factors
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Zusammenfassung:	Plasma concentrations of serum amyloid A (SAA), high density lipoprotein (HDL) cholesterol, non-HDL cholesterol, and apolipoproteins (Apo) A-I and B were measured daily for 6 days in 10 patients following myocardial infarction (MI) and in 10 secular controls admitted to a coronary care unit. SAA concentrations peaked 3 days following MI (mean 47 mg/dl) and correlated with creatine kinase (CK) ( r = 0.67, P < 0.001). Non-HDL cholesterol and Apo B fell 15 and 18%, respectively, reached nadirs 3–4 days after MI and were inversely related to CK concentrations ( P
ISSN:	0009-8981 1873-3492
DOI:	10.1016/0009-8981(89)90063-6