The comparative activity of lomefloxacin (SC-47111, NY-198) and other orally absorbable agents against Haemophilus influenzae and Branhamella catarrhalis

We compared the in vitro activity of lomefloxacin with that of other agents against 336 strains of Haemophilus influenzae and Branhamella catarrhalis isolated from the respiratory tract of a predominantly adult and in-patient population. H. influenzae strains were usually not serotypable. No strains...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 1989-09, Vol.12 (5), p.437-440
Hauptverfasser:	Forward, K.R., Degagne, P.A., Bartlett, K.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Quinolones Action of physical and chemical agents on bacteria Administration, Oral Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Bacteriology Biological and medical sciences Fluoroquinolones Fundamental and applied biological sciences. Psychology Haemophilus influenzae - drug effects Humans Microbiology Moraxella (Branhamella) catarrhalis - drug effects Quinolones
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Zusammenfassung:	We compared the in vitro activity of lomefloxacin with that of other agents against 336 strains of Haemophilus influenzae and Branhamella catarrhalis isolated from the respiratory tract of a predominantly adult and in-patient population. H. influenzae strains were usually not serotypable. No strains were resistant to lomefloxacin; all strains tested were susceptible to 0.25 μg/ml. The lomefloxacin MIC 50 and MIC 90 was 0.125 μg/ml.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/0732-8893(89)90116-8