Equivalent multi-tissue and thermodynamic decompression algorithms

Multi-tissue and thermodynamic decompression algorithms are described and a computational equivalence is established between the two approaches. Eigenvalues and weighted eigenfunctions of the Fick-Fourier equation effectively define response functions from which Haldane half-lives can be extracted f...

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Veröffentlicht in:International journal of bio-medical computing 1989-12, Vol.24 (4), p.227-245
1. Verfasser: Wienke, B.R.
Format: Artikel
Sprache:eng
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Zusammenfassung:Multi-tissue and thermodynamic decompression algorithms are described and a computational equivalence is established between the two approaches. Eigenvalues and weighted eigenfunctions of the Fick-Fourier equation effectively define response functions from which Haldane half-lives can be extracted from arbitrary exposures, operationally bridging the two approaches. Decompression criteria for the algorithms are also described and coupled. Comparisons of similarities and differences of approaches are given from both theoretical and applied viewpoints. A seven-parameter set, spanning both models, forms the basis of analysis. We find that representative thermodynamic parameters in a perfusion-diffusion model effectively recover Haldane half-lives in a bootstrap and that critical parameters overlap, though ranges differ in the two cases.
ISSN:0020-7101
DOI:10.1016/0020-7101(89)90019-6