Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives: Orally Active, Potent, and Selective Prostaglandin D2 Receptor Antagonists

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Veröffentlicht in:	Journal of medicinal chemistry 1997-10, Vol.40 (22), p.3504-3507
Hauptverfasser:	Tsuri, Tatsuo, Honma, Tsunetoshi, Hiramatsu, Yoshiharu, Okada, Toshihiko, Hashizume, Hiroshi, Mitsumori, Susumu, Inagaki, Masanao, Arimura, Akinori, Yasui, Kiyoshi, Asanuma, Fujio, Kishino, Junji, Ohtani, Mitsuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Blood Platelets - drug effects Bones, joints and connective tissue. Antiinflammatory agents Bridged Bicyclo Compounds - administration & dosage Bridged Bicyclo Compounds - chemistry Bridged Bicyclo Compounds - pharmacology Guinea Pigs Humans Medical sciences Norbornanes - administration & dosage Norbornanes - chemistry Norbornanes - pharmacology Pharmacology. Drug treatments Prostaglandin D2 - metabolism Receptors, Immunologic Receptors, Prostaglandin - administration & dosage Receptors, Prostaglandin - metabolism Stereoisomerism Structure-Activity Relationship
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