Cerebral oxygenation during warming after cardiopulmonary bypass

OBJECTIVES To evaluate jugular venous oxygen saturation (SjvO2), measured with a fiberoptic oximetry catheter, and brain tissue oxygen saturation, measured by near-infrared spectroscopy (NIRSO2), as monitors of cerebral oxygenation during cardiopulmonary bypass surgery. DESIGN Prospective, clinical study. SETTING Operating room of a Veterans Administration Hospital. PATIENTS Nineteen patients undergoing moderate hypothermic cardiopulmonary bypass surgery. INTERVENTIONS SjvO2 and NIRSO2 were monitored in the patients during the surgical procedure. MEASUREMENTS AND MAIN RESULTS Moderate hypothermic cardiopulmonary bypass surgery had two distinct cerebral hemodynamic phases. While the patients were hypothermic, SjvO2 averaged 80 +/- 7% and none of the patients had an increase in cerebral lactate production. During the rewarming period, however, reductions in SjvO2 to