Individual differences in auditory middle latency responses in elderly adults and patients with Alzheimer's disease

Previous research has suggested that the Pb component of the middle-latency auditory evoked response (MLAER) is differentially abnormal in patients with Alzheimer's disease relative to control subjects. In the present study, this putative abnormality was examined in vertex-recorded MLAERs elici...

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Veröffentlicht in:	International journal of psychophysiology 1997-09, Vol.27 (2), p.125-136
Hauptverfasser:	Phillips, Natalie A, F. Connolly, John, Charles Mate-Kole, C, Gray, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Adult Aged - psychology Aging Alzheimer Disease - psychology Alzheimer's disease Auditory Double-Blind Method Electroencephalography Electrooculography Evoked potentials Evoked Potentials, Auditory - physiology Female Humans Individual differences Individuality Male Middle-latency auditory evoked response (MLAER) Reaction Time - physiology Sex Characteristics Sex differences
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Zusammenfassung:	Previous research has suggested that the Pb component of the middle-latency auditory evoked response (MLAER) is differentially abnormal in patients with Alzheimer's disease relative to control subjects. In the present study, this putative abnormality was examined in vertex-recorded MLAERs elicited by monaural stimulation in 14 patients with Alzheimer's disease (six females) and 22 age-matched control subjects (10 females). A sex difference in Pb elicitation was revealed in control subjects; Pb area was twice as large in females than males ( P
ISSN:	0167-8760 1872-7697
DOI:	10.1016/S0167-8760(97)00051-2