Evaluation of four Narcissus Cultivars as Potential Sources for Galanthamine Production

Abstract Galanthamine, an alkaloid present in the Amaryllidaceae is currently undergoing clinical trials for the treatment of Alzheimer's. Common daffodils, NARCISSUS spp., contain galanthamine and other alkaloids. Four commercial NARCISSUS cultivars were evaluated as potential sources of galan...

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Veröffentlicht in:	Planta medica 1997-10, Vol.63 (5), p.472-474
Hauptverfasser:	Moraes-Cerdeira, Rita M., Burandt, Charles L., Bastos, Jairo K., Nanayakkara, N. P. Dhammika, Mikell, Julie, Thurn, Jeffrey, McChesney, James D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Biological and medical sciences Galantamine - biosynthesis Galantamine - isolation & purification Galantamine - therapeutic use General pharmacology Humans Letters Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots Plants, Medicinal - classification Plants, Medicinal - metabolism
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Zusammenfassung:	Abstract Galanthamine, an alkaloid present in the Amaryllidaceae is currently undergoing clinical trials for the treatment of Alzheimer's. Common daffodils, NARCISSUS spp., contain galanthamine and other alkaloids. Four commercial NARCISSUS cultivars were evaluated as potential sources of galanthamine. Planting depths, planting densities, bulb size or flower bud removal did not affect galanthamine content.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2006-957740