Effect of substance P on thyrotropin secretion from the pituitary gland in the rat

The role of substance P (SP) on thyrotropin (TSH) secretion was investigated in ovariectomized (OVX) female, estrogen-primed OVX, and normal male rats. Third ventricular administration of SP induced a significant increase in plasma TSH levels when compared to control animals in E-primed OVX rats ( p

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1989-07, Vol.10 (4), p.763-766
Hauptverfasser:	Arisawa, Masayoshi, Snyder, Gary D., McCann, Samuel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Estrogen priming Female Fundamental and applied biological sciences. Psychology Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis In Vitro Techniques Injections, Intravenous Injections, Intraventricular Male Ovariectomy Pituitary gland Pituitary Gland - drug effects Pituitary Gland - metabolism Pituitary Gland, Anterior - cytology Pituitary Gland, Anterior - drug effects Pituitary Gland, Anterior - metabolism Rats Rats, Inbred Strains Substance P Substance P - pharmacology Thyrotropin - blood Thyrotropin - metabolism Thyrotropin secretion Time Factors Vertebrates: endocrinology
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Zusammenfassung:	The role of substance P (SP) on thyrotropin (TSH) secretion was investigated in ovariectomized (OVX) female, estrogen-primed OVX, and normal male rats. Third ventricular administration of SP induced a significant increase in plasma TSH levels when compared to control animals in E-primed OVX rats ( p
ISSN:	0196-9781 1873-5169
DOI:	10.1016/0196-9781(89)90110-1