A MODEL TO TEST THE POTENCY OF INHALATION ANAESTHETICS

The water flea Daphnia magna was studied as a potential model of the potency of inhalation anaesthetics in humans. Anaesthesia was defined as lack of movement to a noxious stimulus (strong light). Effective concentrations which produced anaesthesia of 50% of the individuals (EC50) for halothane, iso...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1989-10, Vol.63 (4), p.489-491
Hauptverfasser:	MCKENZIE, J. DOUGLAS, CALOW, PETER, NIMMO, WALTER S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia, Inhalation Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Daphnia - drug effects Dose-Response Relationship, Drug Enflurane - pharmacology Halothane - pharmacology Isoflurane - pharmacology Light Medical sciences Models, Biological Movement - drug effects Neuropharmacology Pharmacology. Drug treatments
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