The medial amygdala is part of a mineralocorticoid-sensitive circuit controlling NaCl intake in the rat

Damage in female rats to the medial region of the amygdala abolished the sodium appetite that is evoked by mineralocorticoids (both aldosterone and deoxycorticosterone) without preventing the sodium appetite induced by body sodium depletion. It also eliminated or reduced the daily-need free saline i...

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Veröffentlicht in:	Behavioural brain research 1989-11, Vol.35 (2), p.127-134
Hauptverfasser:	Nitabach, Michael N., Schulkin, Jay, Epstein, Alan N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - pharmacology Amygdala - drug effects Animals Appetite - drug effects Behavioral psychophysiology Biological and medical sciences Brain Mapping Desoxycorticosterone - pharmacology Female Fundamental and applied biological sciences. Psychology Medial amygdala Mineralocorticoid Na + appetite Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred Strains Sodium Chloride - administration & dosage Water-Electrolyte Balance - drug effects
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Beschreibung
Zusammenfassung:	Damage in female rats to the medial region of the amygdala abolished the sodium appetite that is evoked by mineralocorticoids (both aldosterone and deoxycorticosterone) without preventing the sodium appetite induced by body sodium depletion. It also eliminated or reduced the daily-need free saline intake of the female rat. These results suggest that the medial region of the amygdala is part of a specifically mineralocorticoid-sensitive neural circuit subserving sodium appetite.
ISSN:	0166-4328 1872-7549
DOI:	10.1016/S0166-4328(89)80113-5