Effect of Ca Level on 65Zn Absorption at the Ligated Duodenal Loop of Rat

Effect of Ca Level on 65Zn Absorption at the Ligated Duodenal Loop of Rat Hiromi, GUNSHIN / Hiroshi, NAITO / Tadashi, NOGUCHI / Hidemi, TODORIKl / Takashi, AKAMATSU 1) Dapartment of Preventive Medicine, School of Medicine, University of the Ryukyus. / Department of Agricultural Chemistry, University of Tokyo. Tokyo 113. Japan Effect of calcium concentration on Zn absorption was studied in rats. Administration of Zn solution with calcium through gastric tructs depressed markedly the levels of Zn in serum taken from portal vein. Dependency on calcium concentrations of the absorption and distribution of Ca in the body was determined using in situ administration of Zn into ligated duodenal loop of rats. Administration of Zn with high calcium solution decreased significantly the levels of Zn in serum and all the tissues compared with the administration with low and medium calcium solutions. A considerable desease in the level of Zn was observed in the liver and kidney compared with the rats administered with medium and low calcium solutions.