Retrospective Evaluation of Therapies for Staphylococcus aureus Endocarditis

We retrospectively evaluated antiinfective therapy for methicillin‐sensitive (MSSA) and methicillin‐resistant Staphylococcus aureus (MRSA) endocarditis in 54 patients who had 57 treatment courses for the disease. Three treatments were assessed: 27 nafcillin‐treated courses of MSSA endocarditis, 18 v...

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Veröffentlicht in:	Pharmacotherapy 1997-09, Vol.17 (5), p.990-997
Hauptverfasser:	Gentry, Chris A., Rodvold, Keith A., Novak, Richard M., Hershow, Ronald C., Naderer, Odin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Endocarditis, Bacterial - drug therapy Endocarditis, Bacterial - microbiology Female Humans Male Medical sciences Methicillin Resistance - physiology Middle Aged Nafcillin - therapeutic use Pharmacology. Drug treatments Retrospective Studies Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Treatment Outcome Vancomycin - therapeutic use
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Zusammenfassung:	We retrospectively evaluated antiinfective therapy for methicillin‐sensitive (MSSA) and methicillin‐resistant Staphylococcus aureus (MRSA) endocarditis in 54 patients who had 57 treatment courses for the disease. Three treatments were assessed: 27 nafcillin‐treated courses of MSSA endocarditis, 18 vancomycin‐treated courses of MSSA endocarditis, and 11 vancomycin‐treated courses of MRSA endocarditis. At baseline, patients with MSSA treated with vancomycin had more chronic conditions (p
ISSN:	0277-0008 1875-9114
DOI:	10.1002/j.1875-9114.1997.tb03788.x