Low-antigen-content diet in the treatment of patients with mixed cryoglobulinemia

The effects of a low-antigen-content diet (LAC diet) versus a standard normocaloric diet on the signs and symptoms of mixed cryoglobulinemia (MC) were compared in a crossover randomized study. The study consisted of 24 outpatients with MC, and was carried out in a 48-week period. After 18 weeks of e...

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Veröffentlicht in:The American journal of medicine 1989-11, Vol.87 (5), p.519-524
Hauptverfasser: Ferri, Clodoveo, Pietrogrande, Maurizio, Cecchetti, Riccardo, Tavoni, Antonio, Cefalo, Alberto, Buzzetti, Giampiero, Vitali, Claudio, Bombardieri, Stefano
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Sprache:eng
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Zusammenfassung:The effects of a low-antigen-content diet (LAC diet) versus a standard normocaloric diet on the signs and symptoms of mixed cryoglobulinemia (MC) were compared in a crossover randomized study. The study consisted of 24 outpatients with MC, and was carried out in a 48-week period. After 18 weeks of either the LAC or the placebo diet, patients returned to a totally unrestricted diet for 12 weeks (washout period) and crossed over to the second half of the study for the other 18 weeks. After three weeks of the restricted LAC diet, the cryocrit decreased from 3.5 ± 3.4% (mean ± SD) to 2.3 ± 2.0% (p
ISSN:0002-9343
1555-7162
DOI:10.1016/S0002-9343(89)80607-2