Neisseria gonorrhoeae: vaginal clearance and its correlation with resistance to infection in subcutaneous chambers in orally immunized estradiol-primed mice

Neisseria gonorrhoeae: vaginal clearance and its correlation with resistance to infection in subcutaneous chambers in orally immunized estradiol-primed mice

The rate of clearance of Neisseria gonorrhoeae in vaginal specimens harvested from inbred Balb/c and outbred (Institute of Cancer Research [ICR]) white mice, previously primed with saline or β-estradiol and then challenged with live gonococci, was determined. Survival of gonococci was significantly...

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Veröffentlicht in:Vaccine 1997-08, Vol.15 (12), p.1344-1348
Hauptverfasser: Arko, Robert J., Smith, Saralyn, Chen, Cheng Y.
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Animals
Bacterial Vaccines - immunology
Bacteriology
Biological and medical sciences
Estradiol - pharmacology
Female
Fundamental and applied biological sciences. Psychology
Gonorrhea - immunology
Immunization
Mice
Mice, Inbred BALB C
Mice, Inbred ICR
Microbiology
Neisseria gonorrhoeae
Niesseria oral immunization
Skin - microbiology
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Vagina - microbiology
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Zusammenfassung:The rate of clearance of Neisseria gonorrhoeae in vaginal specimens harvested from inbred Balb/c and outbred (Institute of Cancer Research [ICR]) white mice, previously primed with saline or β-estradiol and then challenged with live gonococci, was determined. Survival of gonococci was significantly ( P
ISSN:0264-410X
1873-2518
DOI:10.1016/S0264-410X(97)00035-2