An Autopsied Case of Disseminated Cryptococcosis with Marked Lymphadenopathy

A 75 year old woman who was admitted to Higashisaga National Hospital due to chronic bronchitis showed a high fever (39.2°C) and marked lymphadenopathy of the bilateral inguinal lymphnodes. Chest X-ray showed diffuse infiltration. Cryptococcus was detected in biopsied lymphnodes. Although 5-fluorocytosine, miconazole, amphotericine-B were administered for six weeks, she died and an autopsy was performed. Disseminated cryptococcosis was observed in the lung, liver, spleen, kindey, bone marrow, and lymphnodes of the lung hilum, paratrachea, retroperitoneum, gall bladder and groin. She was a human T cell leukemia type I (HTLV-I) carrier, and this could be related to disseminated cryptococcosis.