Cognition and mood in systemic lupus erythematosus. Evaluation and pathogenesis

Cognitive dysfunction is frequent in SLE, probably related to primary underlying immune/inflammatory mechanisms operating in the brain. Longitudinal studies relating patterns of cognitive impairment to putative pathogenetic factors would provide evidence for this hypothesis. Such studies could also...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1997-08, Vol.823, p.44-59
Hauptverfasser:	Denburg, S D, Carbotte, R M, Denburg, J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Affect - physiology Cognition - physiology Cognition Disorders - diagnosis Humans Lupus Erythematosus, Systemic - psychology Mood Disorders - diagnosis Neuropsychological Tests
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Zusammenfassung:	Cognitive dysfunction is frequent in SLE, probably related to primary underlying immune/inflammatory mechanisms operating in the brain. Longitudinal studies relating patterns of cognitive impairment to putative pathogenetic factors would provide evidence for this hypothesis. Such studies could also lead to more specific therapeutic interventions to ameliorate or reverse brain compromise in SLE.
ISSN:	0077-8923
DOI:	10.1111/j.1749-6632.1997.tb48378.x