Numerical aberration of chromosome 17 is correlated with multiple primary cancer in colorectal carcinoma

Numerical aberration of chromosome 17 of 14 cases of colorectal carcinoma with multiple primary cancer (: multiple cancer) was compaired with that of 35 cases of colorectal carcinoma without any other cancer (: single cancer). Fluorescence in situ hybridization with p17H8 was performed on touch smea...

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Veröffentlicht in:	Nippon Shokakibyo Gakkai Zasshi 1997/07/05, Vol.94(7), pp.464-468
Hauptverfasser:	SAWAI, Terumitsu, SASANO, Osamu, TSUJI, Takashi, NANASHIMA, Atsushi, YASUTAKE, Toru, KUSANO, Hiroyuki, TAGAWA, Yutaka, NAKAGOE, Tohru, AYABE, Hiroyoshi
Format:	Artikel
Sprache:	jpn
Schlagworte:	Aged Chromosome Aberrations Chromosomes, Human, Pair 17 Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Female fluorescence in situ hybridization Humans In Situ Hybridization, Fluorescence Lymphatic Metastasis Male Neoplasms, Multiple Primary - genetics Stomach Neoplasms - genetics
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Zusammenfassung:	Numerical aberration of chromosome 17 of 14 cases of colorectal carcinoma with multiple primary cancer (: multiple cancer) was compaired with that of 35 cases of colorectal carcinoma without any other cancer (: single cancer). Fluorescence in situ hybridization with p17H8 was performed on touch smear from fresh materials. The proportion of aneusomy 17 (NCAI: numerical chromosome aberration index) in multiple cancers was significantly higher than that of single cancers (37.7±10.5% VS 46.1±8.0%; p
ISSN:	0446-6586 1349-7693
DOI:	10.11405/nisshoshi1964.94.7_464