Dopaminergic behaviour in chicken retina and the effect of form deprivation

ABSTRACT Purpose: Dopamine (DA)is cinsidered to be a neurotransmitter involved in light‐adaptive responses in the retina and has been implicated in the control of the eye growth include by form deprivation vitreal DOPAC was shown to be a good indicator of retinal dopaminergic activity. Methods/Resul...

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Veröffentlicht in:Australian and New Zealand journal of ophthalmology 1997-11, Vol.25 (4), p.76-78
Hauptverfasser: Megaw, PL, Morgan, IG, Boelen, MK
Format: Artikel
Sprache:eng
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Zusammenfassung:ABSTRACT Purpose: Dopamine (DA)is cinsidered to be a neurotransmitter involved in light‐adaptive responses in the retina and has been implicated in the control of the eye growth include by form deprivation vitreal DOPAC was shown to be a good indicator of retinal dopaminergic activity. Methods/Results: Dopaminergic activity was highest during the light, with vitreal DOPAC levels rising within in 3 hof light exposure. Form deperivation attenuated dopaminergic activity, as the rise in vitreal DOPAC levels on light exposure was rediced in form‐depeived eyes, compared with control eyes. Conclusion: The lack sustained activation of DA release may explain the role of DA in the control of eye‐growth.
ISSN:0814-9763
1440-1606
DOI:10.1111/j.1442-9071.1997.tb01764.x