Serological evidence for active Epstein-Barr virus infection in multifocal choroiditis

Six patients, consisting of 4 males and 2 females with mean average age fo 29.20 years, with variable picture of multifocal choroiditis were serologically investigated for their association with Epstein-Barr Virus (EBV) infection. IgG and IgM antibodies to EBV-Virus Capsid Antigen (VCA) were assayed...

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Veröffentlicht in:	Indian journal of pathology & microbiology 1997-04, Vol.40 (2), p.129-131
Hauptverfasser:	Bhende, P S, Biswas, J, Madhavan, H N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Viral - analysis Antigens, Viral - immunology Capsid Proteins Cells, Cultured Choroiditis - virology Female Herpesviridae Infections - blood Herpesviridae Infections - diagnosis Herpesviridae Infections - immunology Herpesvirus 4, Human - immunology Humans Immunoglobulin G - analysis Immunoglobulin M - analysis Male Middle Aged
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Zusammenfassung:	Six patients, consisting of 4 males and 2 females with mean average age fo 29.20 years, with variable picture of multifocal choroiditis were serologically investigated for their association with Epstein-Barr Virus (EBV) infection. IgG and IgM antibodies to EBV-Virus Capsid Antigen (VCA) were assayed by immunoperoxidase method on EBV infected lymphoblast cells (P3HR-1 Burkitt's lymphoma cell line). In these patients definite serological evidence of EBV infection with high titres of IgG and IgM antibodies to EBV-VCA was demonstrated suggestive of active continuing or persisting EBV infection.
ISSN:	0377-4929