Inhibition of normal and psoriatic epidermal phospholipase A2 by picomolar concentrations of recombinant human lipocortin I

SUMMARY Normal human and psoriatic epidermal phospholipase A2 (PLA2) was inhibited by human recombinant lipocortin I when the substrate was present in a several million‐fold molar excess. Inhibition was not total, even at relatively high concentrations of lipocortin I. It is therefore suggested that...

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Veröffentlicht in:British journal of dermatology (1951) 1989-08, Vol.121 (2), p.155-160
Hauptverfasser: CARTWRIGHT, P.H., ILDERTON, E., SOWDEN, J.M., YARDLEY, H.J.
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Sprache:eng
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