FeLV-FAIDS-induced immunodeficiency syndrome in cats
Findings are reviewed, relevant to elucidation of the pathogenic, genetic and biochemical properties of a single, genetically heterogeneous isolate of feline leukemia virus (FeLV-FAIDS) shown to induce fatal immunodeficiency disease in nearly 100% of inoculated cats. Hypotheses are suggested which p...
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| Veröffentlicht in: | Veterinary immunology and immunopathology 1989-05, Vol.21 (1), p.25-37 |
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| container_end_page | 37 |
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| container_issue | 1 |
| container_start_page | 25 |
| container_title | Veterinary immunology and immunopathology |
| container_volume | 21 |
| creator | Mullins, James I. Hoover, Edward A. Overbaugh, Julie Quackenbush, Sandra L. Donahue, Peter R. Poss, Mary L. |
| description | Findings are reviewed, relevant to elucidation of the pathogenic, genetic and biochemical properties of a single, genetically heterogeneous isolate of feline leukemia virus (FeLV-FAIDS) shown to induce fatal immunodeficiency disease in nearly 100% of inoculated cats. Hypotheses are suggested which pertain to the mechanism of T-cell killing by this virus, and which extrapolate findings in the FeLV-FAIDS animal model to AIDS induced in humans by human immunodeficiency virus (HIV). |
| doi_str_mv | 10.1016/0165-2427(89)90127-X |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Veterinary immunology and immunopathology, 1989-05, Vol.21 (1), p.25-37 |
| issn | 0165-2427 1873-2534 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acquired Immunodeficiency Syndrome AIDS/HIV Animals Cat Diseases - immunology Cat Diseases - microbiology Cats Disease Models, Animal feline leukemia virus Genes, Viral Immunologic Deficiency Syndromes - immunology Immunologic Deficiency Syndromes - microbiology Immunologic Deficiency Syndromes - veterinary Leukemia - immunology Leukemia - microbiology Leukemia - veterinary Leukemia Virus, Feline - genetics Leukemia Virus, Feline - immunology Leukemia Virus, Feline - isolation & purification Leukemia Virus, Feline - pathogenicity Retroviridae Infections - immunology Retroviridae Infections - microbiology Retroviridae Infections - veterinary |
| title | FeLV-FAIDS-induced immunodeficiency syndrome in cats |
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