Influence of immunization with allogeneic spleen cells on the number of viable neonates in mice

Female CBA/J (H-2 k) mice mated with male DBA/2J (H-2 d) mice show a high level of fetal resorption, which can be reduced by immunization with BALB/c (H-2 d) spleen cells. The morphologically defined fetal resorption rate upon which evaluation of the outcome of pregnancy has previously been based in...

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Veröffentlicht in:	Journal of reproductive immunology 1989-05, Vol.15 (2), p.169-173
Hauptverfasser:	Heine, O., Neppert, J., Mueller-Eckhardt, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - immunology Abortion, Habitual - therapy Animals Biological and medical sciences Disease Models, Animal - therapy Diseases of mother, fetus and pregnancy Female Fetal Death - therapy Fetal Resorption - therapy Fetus - immunology Gynecology. Andrology. Obstetrics Immune Tolerance Immunization immunology of abortion Isoantigens - therapeutic use Litter Size Medical sciences Mice Mice, Inbred BALB C - immunology Mice, Inbred CBA - immunology Mice, Inbred DBA - immunology murine fetal resorption Pregnancy Pregnancy. Fetus. Placenta Spleen - immunology
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Zusammenfassung:	Female CBA/J (H-2 k) mice mated with male DBA/2J (H-2 d) mice show a high level of fetal resorption, which can be reduced by immunization with BALB/c (H-2 d) spleen cells. The morphologically defined fetal resorption rate upon which evaluation of the outcome of pregnancy has previously been based in this strain combination is not equivalent to the rate of production of viable neonates.
ISSN:	0165-0378 1872-7603
DOI:	10.1016/0165-0378(89)90036-3