Electroretinographic findings in Fuchs' heterochromic cyclitis
Purpose: Fuchs' heterochromic cyclitis (FHC) is an inflammatory disease of unknown aetiology. Although anterior segment signs and vitreous changes are well recognised, retinal features are unusual. To assess the extent of retinal involvement, we performed electrophysiological testing in a group...
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Veröffentlicht in: | Eye (London) 1997-01, Vol.11 (1), p.102-108 |
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creator | Murray, D C Stavrou, P Good, P A Murray, P I |
description | Purpose:
Fuchs' heterochromic cyclitis (FHC) is an inflammatory disease of unknown aetiology. Although anterior segment signs and vitreous changes are well recognised, retinal features are unusual. To assess the extent of retinal involvement, we performed electrophysiological testing in a group of FHC patients.
Methods:
Retinal function was assessed by means of flash electroretinogram (ERG) using a Ganzfeld stimulus, and pattern electroretinogram (PERG) using a checkerboard stimulus of spatial frequency 0.5 and 1.0 cycle per degree reversing at 6 Hz. A total of 21 patients with unilateral, normotensive FHC with visual acuities of 6/5 to 6/9 were studied.
Results:
In the flash ERG, selective scotopic b-wave abnormalities occurred in 9 (43%) of 21 FHC eyes. Despite clear media and no history of ocular surgery, 7 patients showed abnormalities of the PERG.
Conclusions:
These electrophysiological findings suggest subclinical damage to the inner retinal layers, but not involving the photoreceptors, in eyes with FHC. |
doi_str_mv | 10.1038/eye.1997.20 |
format | Article |
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Fuchs' heterochromic cyclitis (FHC) is an inflammatory disease of unknown aetiology. Although anterior segment signs and vitreous changes are well recognised, retinal features are unusual. To assess the extent of retinal involvement, we performed electrophysiological testing in a group of FHC patients.
Methods:
Retinal function was assessed by means of flash electroretinogram (ERG) using a Ganzfeld stimulus, and pattern electroretinogram (PERG) using a checkerboard stimulus of spatial frequency 0.5 and 1.0 cycle per degree reversing at 6 Hz. A total of 21 patients with unilateral, normotensive FHC with visual acuities of 6/5 to 6/9 were studied.
Results:
In the flash ERG, selective scotopic b-wave abnormalities occurred in 9 (43%) of 21 FHC eyes. Despite clear media and no history of ocular surgery, 7 patients showed abnormalities of the PERG.
Conclusions:
These electrophysiological findings suggest subclinical damage to the inner retinal layers, but not involving the photoreceptors, in eyes with FHC.</description><identifier>ISSN: 0950-222X</identifier><identifier>EISSN: 1476-5454</identifier><identifier>DOI: 10.1038/eye.1997.20</identifier><identifier>PMID: 9246286</identifier><identifier>CODEN: EYEEEC</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Electroretinography - methods ; Female ; Humans ; Iridocyclitis - complications ; Iridocyclitis - physiopathology ; Laboratory Medicine ; Lenses, Intraocular ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Ophthalmology ; Pharmaceutical Sciences/Technology ; Reaction Time ; Retinal Diseases - diagnosis ; Retinal Diseases - etiology ; Surgery ; Surgical Oncology ; Uvea diseases ; Visual Acuity</subject><ispartof>Eye (London), 1997-01, Vol.11 (1), p.102-108</ispartof><rights>Royal College of Ophthalmologists 1997</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-e0bbe5625f9b55aedd29f3923caba31e8c9e0fae7457bd68271a54c7fbda80813</citedby><cites>FETCH-LOGICAL-c387t-e0bbe5625f9b55aedd29f3923caba31e8c9e0fae7457bd68271a54c7fbda80813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/eye.1997.20$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/eye.1997.20$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,4010,27900,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2662150$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9246286$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Murray, D C</creatorcontrib><creatorcontrib>Stavrou, P</creatorcontrib><creatorcontrib>Good, P A</creatorcontrib><creatorcontrib>Murray, P I</creatorcontrib><title>Electroretinographic findings in Fuchs' heterochromic cyclitis</title><title>Eye (London)</title><addtitle>Eye</addtitle><addtitle>Eye (Lond)</addtitle><description>Purpose:
Fuchs' heterochromic cyclitis (FHC) is an inflammatory disease of unknown aetiology. Although anterior segment signs and vitreous changes are well recognised, retinal features are unusual. To assess the extent of retinal involvement, we performed electrophysiological testing in a group of FHC patients.
Methods:
Retinal function was assessed by means of flash electroretinogram (ERG) using a Ganzfeld stimulus, and pattern electroretinogram (PERG) using a checkerboard stimulus of spatial frequency 0.5 and 1.0 cycle per degree reversing at 6 Hz. A total of 21 patients with unilateral, normotensive FHC with visual acuities of 6/5 to 6/9 were studied.
Results:
In the flash ERG, selective scotopic b-wave abnormalities occurred in 9 (43%) of 21 FHC eyes. Despite clear media and no history of ocular surgery, 7 patients showed abnormalities of the PERG.
Conclusions:
These electrophysiological findings suggest subclinical damage to the inner retinal layers, but not involving the photoreceptors, in eyes with FHC.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Electroretinography - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Iridocyclitis - complications</subject><subject>Iridocyclitis - physiopathology</subject><subject>Laboratory Medicine</subject><subject>Lenses, Intraocular</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Reaction Time</subject><subject>Retinal Diseases - diagnosis</subject><subject>Retinal Diseases - etiology</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Uvea diseases</subject><subject>Visual Acuity</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM1LwzAYh4Moc05PnoUeRA_amaRN01wEGfMDBl4UvIU0fbNmtOlM2sP-eztWdvL0Hp6H3wsPQtcEzwlO8ifYwZwIwecUn6ApSXkWs5Slp2iKBcMxpfTnHF2EsMF4gBxP0ETQNKN5NkXPyxp051sPnXXt2qttZXVkrCutW4fIuui111W4jyrowLe68m0zCHqna9vZcInOjKoDXI13hr5fl1-L93j1-faxeFnFOsl5FwMuCmAZZUYUjCkoSypMImiiVaESArkWgI0CnjJelFlOOVEs1dwUpcpxTpIZujvsbn3720PoZGODhrpWDto-SC4ITzCng_hwELVvQ_Bg5NbbRvmdJFjua8mhltzXkhQP9s042xcNlEd3zDPw25GroFVtvHLahqNGs4wStp95PGhhIG4NXm7a3rshyL9f_wAd8IH9</recordid><startdate>19970101</startdate><enddate>19970101</enddate><creator>Murray, D C</creator><creator>Stavrou, P</creator><creator>Good, P A</creator><creator>Murray, P I</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19970101</creationdate><title>Electroretinographic findings in Fuchs' heterochromic cyclitis</title><author>Murray, D C ; Stavrou, P ; Good, P A ; Murray, P I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-e0bbe5625f9b55aedd29f3923caba31e8c9e0fae7457bd68271a54c7fbda80813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Electroretinography - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Iridocyclitis - complications</topic><topic>Iridocyclitis - physiopathology</topic><topic>Laboratory Medicine</topic><topic>Lenses, Intraocular</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Reaction Time</topic><topic>Retinal Diseases - diagnosis</topic><topic>Retinal Diseases - etiology</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Uvea diseases</topic><topic>Visual Acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Murray, D C</creatorcontrib><creatorcontrib>Stavrou, P</creatorcontrib><creatorcontrib>Good, P A</creatorcontrib><creatorcontrib>Murray, P I</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Murray, D C</au><au>Stavrou, P</au><au>Good, P A</au><au>Murray, P I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electroretinographic findings in Fuchs' heterochromic cyclitis</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><addtitle>Eye (Lond)</addtitle><date>1997-01-01</date><risdate>1997</risdate><volume>11</volume><issue>1</issue><spage>102</spage><epage>108</epage><pages>102-108</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><coden>EYEEEC</coden><abstract>Purpose:
Fuchs' heterochromic cyclitis (FHC) is an inflammatory disease of unknown aetiology. Although anterior segment signs and vitreous changes are well recognised, retinal features are unusual. To assess the extent of retinal involvement, we performed electrophysiological testing in a group of FHC patients.
Methods:
Retinal function was assessed by means of flash electroretinogram (ERG) using a Ganzfeld stimulus, and pattern electroretinogram (PERG) using a checkerboard stimulus of spatial frequency 0.5 and 1.0 cycle per degree reversing at 6 Hz. A total of 21 patients with unilateral, normotensive FHC with visual acuities of 6/5 to 6/9 were studied.
Results:
In the flash ERG, selective scotopic b-wave abnormalities occurred in 9 (43%) of 21 FHC eyes. Despite clear media and no history of ocular surgery, 7 patients showed abnormalities of the PERG.
Conclusions:
These electrophysiological findings suggest subclinical damage to the inner retinal layers, but not involving the photoreceptors, in eyes with FHC.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>9246286</pmid><doi>10.1038/eye.1997.20</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Biological and medical sciences Electroretinography - methods Female Humans Iridocyclitis - complications Iridocyclitis - physiopathology Laboratory Medicine Lenses, Intraocular Male Medical sciences Medicine Medicine & Public Health Middle Aged Ophthalmology Pharmaceutical Sciences/Technology Reaction Time Retinal Diseases - diagnosis Retinal Diseases - etiology Surgery Surgical Oncology Uvea diseases Visual Acuity |
title | Electroretinographic findings in Fuchs' heterochromic cyclitis |
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